NIFTY – Fetal DNA testing

FAQ

• What are the major advantages of NIFTY fetal DNA testing?

  
  

  • Based on clinical trials, NIFTY is the most accurate test of its kind.
  • NIFTY-Extended is the most comprehensive test of its kind and the only test that examines all 23 pairs of the fetal chromosomes. Thus far, the test has identified more than 90 syndromes.
  • NIFTY is a noninvasive test that poses no risk to the mother or the fetus and can be done as early as the 10th week of the pregnancy.
  • The NIFTY test is conducted at BGI laboratories, the most sophisticated and experienced laboratories of theis kind in the world.

• Is the NIFTY test accurate?

  BGI have conducted a series of clinical trials to determine the accuracy of the NIFTY test. These trials showed a 100% accuracy rate with regards to identifying fetuses with Down syndrome, Edwards syndrome and Patau syndrome. Nevertheless, due to the innovativeness of the test, and to be on the safe side, the test is currently defined as a screening test with an accuracy rate of above 99%. The accuracy rate of the NIFTY-Extended test regarding less common disorders is still being studied and has yet to be determined.

• Does a NIFTY test replace an AFP test?

  The NIFTY test is significantly more accurate than an Alpha Fetoprotein test when it comes to identifying Down syndrome (Edwards syndrome and Patau syndrome, too). Thus, with regard to such conditions, the NIFTY test certainly can replace an AFP test. However, an AFP test can indicate risks associated with defects for which the NIFTY does not test, such as spina bifida. Therefore, it is advisable to carry out an AFP test even if one decides to undergo the NIFTY test.

• Does the NIFTY test replace nuchal translucency screening or a fetal ultrasound?

  The NIFTY test does not replace these tests as it does not test for all the defects covered by such examinations.

• Are there instances in which the NIFTY test is not advisable?

  In all instances, it is advisable to consult with your physician to determine which tests would be most appropriate for you.  The test is inadvisable in the event that one of the parents is known to suffer from chromosomal translocations or any other chromosomal structural disorder. A recent blood-transfusion should be stated when scheduling an appointment.

• Does the test require any preparation beforehand?

  The test does not require any preparation. Just please set an appointment ahead (1-700-700-880).

• When is the NIFTY test carried out?

  The test can be carried out from week 10 of the pregnancy and through to the end of term. It is advisable, however, to conduct the test only up to week 24 so that the results can still be of benefit to the patient. You will need to consult with your physician to receive a referral for the test beyond week 24.

• Why is the blood sample drawn on a specific day and at a specific time?

  As aforesaid, the blood samples are sent for analysis abroad; the testing times are therefore coordinated with the dispatch times.

• When are the results available?

  In general, results are received within ten days. Very rarely technical reasons may require retesting. Obviously, in such rare instances results may be delayed further.

• What is the difference between NIFTY-Basic and NIFTY-Extended?

  NIFTY-Basic tests for the most common trisomies (Down syndrome, Edwards syndrome and Patau syndrome) and the sex chromosomes. NIFTY-Extended in addition tests all 23 pairs of the fetal chromosomes and can also identify duplications or deletions (NIFTY-Extended has successfully identified more than 90 syndromes thus far).